CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization

The choroid, which provides vascular supply to the outer retina, demonstrates progressive degeneration in aging and age-related macular degeneration (AMD). However mechanisms that maintain or compromise choroidal homeostasis are obscure. We discovered that the ablation of choroidal macrophages via C...

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Main Authors: Xiao Yang, Lian Zhao, Maria M Campos, Mones Abu‐Asab, Davide Ortolan, Nathan Hotaling, Kapil Bharti, Wai T. Wong
格式: Artigo
语言:英语
出版: 2020
在线阅读:https://doi.org/10.7554/elife.55564
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