CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization
The choroid, which provides vascular supply to the outer retina, demonstrates progressive degeneration in aging and age-related macular degeneration (AMD). However mechanisms that maintain or compromise choroidal homeostasis are obscure. We discovered that the ablation of choroidal macrophages via C...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2020
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Acesso em linha: | https://doi.org/10.7554/elife.55564 |
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