Clinical implications of intratumor heterogeneity: challenges and opportunities
Abstract In this review, we highlight the role of intratumoral heterogeneity, focusing on the clinical and biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through complex genetic, epigenetic, and protein modifications that drive phenotypic selection in response to e...
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| Główni autorzy: | , , , , , , , |
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| Format: | Revisão |
| Język: | angielski |
| Wydane: |
2020
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| Dostęp online: | https://doi.org/10.1007/s00109-020-01874-2 https://link.springer.com/content/pdf/10.1007/s00109-020-01874-2.pdf |
| Etykiety: |
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