Metformin upregulates mitophagy in patients with T2DM: A randomized placebo‐controlled study
Abstract Impaired mitochondrial autophagy (mitophagy) and NLRP3 inflammasome activation have been incriminated in the pathogenesis of T2DM. Metformin besides being an insulin sensitizer also induces autophagy; however, its effect on mitophagy and NLRP3 activation in patients with T2DM still remains...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Acesso em linha: | https://doi.org/10.1111/jcmm.14834 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcmm.14834 |
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