Structure of the human BBSome core complex
The BBSome is a heterooctameric protein complex that plays a central role in primary cilia homeostasis. Its malfunction causes the severe ciliopathy Bardet-Biedl syndrome (BBS). The complex acts as a cargo adapter that recognizes signaling proteins such as GPCRs and links them to the intraflagellar...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | anglais |
Publié: |
2020
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Accès en ligne: | https://doi.org/10.7554/elife.53910 |
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