Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function
Regulatory T cells (Tregs) subdue immune responses. Central to Treg activation are changes in lipid metabolism that support their survival and function. Fatty acid binding proteins (FABPs) are a family of lipid chaperones required to facilitate uptake and intracellular lipid trafficking. One family...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | angleščina |
Izdano: |
2019
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Online dostop: | https://doi.org/10.1016/j.cmet.2019.11.021 https://www.cell.com/article/S1550413119306655/pdf |
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