Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

The interplay between a highly polymorphic set of MHC-I alleles and molecular chaperones shapes the repertoire of peptide antigens displayed on the cell surface for T cell surveillance. Here, we demonstrate that the molecular chaperone TAP-binding protein related (TAPBPR) associates with a broad ran...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Andrew C. McShan, Christine A. Devlin, Sarah A. Overall, Jihye Park, Jugmohit Toor, Danai Moschidi, David Flores‐Solis, Hannah Choi, Sarvind Tripathi, Erik Procko, Nikolaos G. Sgourakis
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2019
Mynediad Ar-lein:https://doi.org/10.1073/pnas.1915562116
Tagiau: Ychwanegu Tag
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