Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure

Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failure

Recently, we observed that the specialized proresolving mediator (SPM) entity resolvin D1 activates lipoxin A4/formyl peptide receptor 2 (ALX/FPR2), which facilitates cardiac healing and persistent inflammation is a hallmark of impaired cardiac repair in aging. Splenic leukocyte-directed SPMs are es...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bochra Tourki, Vasundhara Kain, Amanda B. Pullen, Paul C. Norris, Nirav Patel, Pankaj Arora, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade
Médium: Artigo
Jazyk:angličtina
Vydáno: 2019
On-line přístup:https://doi.org/10.1016/j.molmet.2019.10.008
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Internet

https://doi.org/10.1016/j.molmet.2019.10.008

Podobné jednotky