Gene therapy for hereditary hearing loss by SLC26A4 mutations in mice reveals distinct functional roles of pendrin in normal hearing

Rationale: Mutations of SLC26A4 that abrogate pendrin, expressed in endolymphatic sac, cochlea and vestibule, are known to cause autosomal recessive sensorineural hearing loss with enlargement of the membranous labyrinth.This is the first study to demonstrate the feasibility of gene therapy for pend...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Mina Kim, Sung Huhn Kim, Nari Ryu, Ji-Hyun Ma, Ye‐Ri Kim, Jinsei Jung, Chuan‐Jen Hsu, Jae Young Choi, Kyu-Yup Lee, Philine Wangemann, Jinwoong Bok, Un‐Kyung Kim
Формат: Artigo
Язык:английский
Опубликовано: 2019
Online-ссылка:https://doi.org/10.7150/thno.38032
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!