BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors

BRAF mutations have been identified as targetable, oncogenic mutations in many cancers. Given the paucity of treatments for primary brain tumors and the poor prognosis associated with high-grade gliomas, BRAF mutations in glioma are of considerable interest. In this review, we present the spectrum o...

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Bibliografski detalji
Glavni autori: Karisa C. Schreck, Stuart A. Grossman, Christine A. Pratilas
Format: Revisão
Jezik:engleski
Izdano: 2019
Online pristup:https://doi.org/10.3390/cancers11091262
https://www.mdpi.com/2072-6694/11/9/1262/pdf
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