The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 and Promotes Tumorigenesis in Mice
Background & AimsThe histone lysine demethylase 3A (KDM3A) demethylates H3K9me1 and H3K9Me2 to increase gene transcription and is upregulated in tumors, including pancreatic tumors. We investigated its activities in pancreatic cancer cell lines and its regulation of the gene encoding doublecorti...
Zapisane w:
Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Artigo |
Język: | angielski |
Wydane: |
2019
|
Dostęp online: | https://doi.org/10.1053/j.gastro.2019.08.018 http://manuscript.elsevier.com/S0016508519412328/pdf/S0016508519412328.pdf |
Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|