Survival Bias in Mendelian Randomization Studies

It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which instrumental variable (IV)-estimators may become biased in the context of exposures that affect survi...

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Main Authors: Roelof A.J. Smit, Stella Trompet, Olaf M. Dekkers, J. Wouter Jukema, Saskia le Cessie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Acesso em linha:https://doi.org/10.1097/ede.0000000000001072
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