Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial

Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial

Rationale: Less invasive, nonsurgical approaches are needed to treat severe emphysema.Objectives: To evaluate the effectiveness and safety of the Spiration Valve System (SVS) versus optimal medical management.Methods: In this multicenter, open-label, randomized, controlled trial, subjects aged 40 ye...

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Hoofdauteurs: Gerard J. Criner, Antoine Delage, Kirk Voelker, D. Kyle Hogarth, Adnan Majid, Michael Zgoda, Donald R. Lazarus, Roberto F. Casal, Sadia Benzaquen, Robert Holladay, Adam Wellikoff, Karel Calero, Mark J. Rumbak, Paul Branca, Muhanned Abu‐Hijleh, Jorge M. Mallea, Ravi Kalhan, Ashutosh Sachdeva, C. Matthew Kinsey, Carla Lamb, Michael F. Reed, Wissam Abouzgheib, Phillip V. Kaplan, Gregory X. Marrujo, David W. Johnstone, Mario Gasparri, Arturo A. Meade, Christopher A. Hergott, Chakravarthy Reddy, Richard A. Mularski, Amy Hajari Case, Samir Makani, Ray W. Shepherd, Benson Chen, Gregory E. Holt, Simon Martel
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2019
Online toegang:https://doi.org/10.1164/rccm.201902-0383oc
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https://doi.org/10.1164/rccm.201902-0383oc

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