Telomere DNA G-quadruplex folding within actively extending human telomerase
Significance Telomeres protect the ends of linear chromosomes from illicit DNA processing events that threaten genome stability. Guanine-rich telomere DNA repeat sequences are protected by telomere-binding proteins, and are also prone to fold into structures called G quadruplexes (GQs). In highly pr...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2019
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| Accès en ligne: | https://doi.org/10.1073/pnas.1814777116 |
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