Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus

Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus

Dynamic trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptors (AMPARs) to synapses is critical for activity-dependent synaptic plasticity underlying learning and memory, but the identity of key molecular effectors remains elusive. Here, we demonstrate that membrane...

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Main Authors: Stephen D. Glasgow, Simon Labrecque, Ian V. Beamish, Sarah Aufmkolk, Julien Gibon, Dong Cho Han, Stephanie N. Harris, Paul Dufresne, Paul W. Wiseman, R. Anne McKinney, Philippe Séguéla, Paul De Koninck, Edward S. Ruthazer, Timothy E. Kennedy
Formato: Artigo
Idioma:inglés
Publicado: 2018
Acceso en liña:https://doi.org/10.1016/j.celrep.2018.09.028
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https://doi.org/10.1016/j.celrep.2018.09.028

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