Systemic administration of orexin A ameliorates established experimental autoimmune encephalomyelitis by diminishing neuroinflammation
Orexins (hypocretins, Hcrt) A and B are GPCR-binding hypothalamic neuropeptides known to regulate sleep/wake states and feeding behavior. A few studies have shown that orexin A exhibits anti-inflammatory and neuroprotective properties, suggesting that it might provide therapeutic effects in inflamma...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2019
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| 在線閱讀: | https://doi.org/10.1186/s12974-019-1447-y https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-019-1447-y |
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