Systemic administration of orexin A ameliorates established experimental autoimmune encephalomyelitis by diminishing neuroinflammation
Orexins (hypocretins, Hcrt) A and B are GPCR-binding hypothalamic neuropeptides known to regulate sleep/wake states and feeding behavior. A few studies have shown that orexin A exhibits anti-inflammatory and neuroprotective properties, suggesting that it might provide therapeutic effects in inflamma...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Engels |
| Gepubliceerd in: |
2019
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| Online toegang: | https://doi.org/10.1186/s12974-019-1447-y https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-019-1447-y |
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