The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
The architecture of a signaling hub Adenylyl cyclases (ACs) respond to a variety of inputs to generate the signaling molecule cyclic adenosine monophosphate. ACs are regulated by G proteins, which are activated by upstream receptors. Qi et al. determined the structure of bovine membrane AC9 bound to...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2019
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| Accès en ligne: | https://doi.org/10.1126/science.aav0778 https://science.sciencemag.org/content/sci/364/6438/389.full.pdf |
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