Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue

Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage. The etiology of dengue-associated thrombocytopenia is multifactorial and includes increased platelet clearance. The...

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Main Authors: Silvita Fitri Riswari, Rahajeng N. Tunjungputri, Vesla Kullaya, Fadel Muhammad Garishah, Gloria S. R. Utari, Nur Farhanah, Gijs J. Overheul, Bachti Alisjahbana, Muhammad Hussein Gasem, Rolf T. Urbanus, Philip G. de Groot, Dirk J. Lefeber, Ronald P. van Rij, André van der Ven, Quirijn de Mast
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.1371/journal.ppat.1007500
https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007500&type=printable
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