Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages

Abstract Macrophage plasticity is the ability of mononuclear phagocytes to change phenotype, function, and genetic reprogramming upon encounter of specific local stimuli. In the tumor microenvironment, Tumor‐Associated Macrophages (TAMs) acquire an immune‐suppressive and tumor‐promoting phenotype. W...

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Detalhes bibliográficos
Principais autores: Akihiro Maeda, Elisabeth Digifico, Fernando Torres, Alberto Mantovani, Paola Allavena
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Acesso em linha:https://doi.org/10.1002/eji.201847888
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.201847888
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