Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy

Tolerogenic dendritic cells and T-regulatory cells are two immune cell populations with the potential to prevent the onset of the clinical stage of type 1 diabetes and to manage the underlying autoimmunity beginning at the time-at-onset and onwards. Initial phase I trials demonstrated that the admin...

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Главные авторы: Brett E. Phillips, Yésica Garciafigueroa, Carl Engman, Massimo Trucco, Nick Giannoukakis
Формат: Revisão
Язык:английский
Опубликовано: 2019
Online-ссылка:https://doi.org/10.3389/fimmu.2019.00148
https://www.frontiersin.org/articles/10.3389/fimmu.2019.00148/pdf
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