Nuclear genetic regulation of the human mitochondrial transcriptome

Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable vari...

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Detalhes bibliográficos
Main Authors: Aminah T. Ali, Lena Boehme, Guillermo Carbajosa, Vlad C. Seitan, Kerrin S. Small, Alan Hodgkinson
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Acesso em linha:https://doi.org/10.7554/elife.41927
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