MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP
Despite its known role as a secreted neuroprotectant, much of the mesencephalic astrocyte-derived neurotrophic factor (MANF) is retained in the endoplasmic reticulum (ER) of producer cells. There, by unknown mechanisms, MANF plays a role in protein folding homeostasis in complex with the ER-localize...
Gardado en:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | inglés |
| Publicado: |
2019
|
| Acceso en liña: | https://doi.org/10.1038/s41467-019-08450-4 https://www.nature.com/articles/s41467-019-08450-4.pdf |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|