Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation

Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation

Increased free thyroxine (FT4) and decreased thyrotropin are associated with increased risk of atrial fibrillation (AF) in observational studies, but direct involvement is unclear. To evaluate the potential direct involvement of thyroid traits on AF. Study-level mendelian randomization (MR) included...

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Hlavní autoři: Christina Ellervik, Carolina Roselli, Ingrid E. Christophersen, Álvaro Alonso, Maik Pietzner, Collen M. Sitlani, Stella Trompet, Dan E. Arking, Bastiaan Geelhoed, Xiuqing Guo, Marcus E. Kleber, Henry J. Lin, Honghuang Lin, Peter W. Macfarlane, Elizabeth Selvin, Christian M. Shaffer, Albert V. Smith, Niek Verweij, Stefan Weiß, Anne Rentoumis Cappola, Marcus Dörr, Vilmundur Guðnason, Susan R. Heckbert, Simon P. Mooijaart, Winfried März, Bruce M. Psaty, Paul M. Ridker, Dan M. Roden, David J. Stott, Henry Völzke, Emelia J. Benjamin, Graciela Delgado, Patrick T. Ellinor, Georg Homuth, Anna Köttgen, J. Wouter Jukema, Steven A. Lubitz, Samia Mora, Michiel Rienstra, Jerome I. Rotter, M. Benjamin Shoemaker, Nona Sotoodehnia, Kent D. Taylor, Pim van der Harst, Christine M. Albert, Daniel I. Chasman
Médium: Artigo
Jazyk:angličtina
Vydáno: 2019
On-line přístup:https://doi.org/10.1001/jamacardio.2018.4635
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https://doi.org/10.1001/jamacardio.2018.4635

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