Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice

Hemophagocytic lymphohistiocytosis (HLH) has recently been increasingly reported as an important complication after stem cell transplantation, in line with the increase in the number of HLA-mismatched transplantation. Although previous clinical studies have shown an elevation of inflammatory cytokin...

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Main Authors: Satoshi Yoshihara, Yuying Li, Jinxing Xia, Nichole Danzl, Megan Sykes, Yong‐Guang Yang
格式: Artigo
语言:英语
出版: 2019
在线阅读:https://doi.org/10.3389/fimmu.2019.00186
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