Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes
Late endosome-resident interferon-induced transmembrane protein 3 (IFITM3) inhibits fusion of diverse viruses, including Influenza A virus (IAV), by a poorly understood mechanism. Despite the broad antiviral activity of IFITM3, viruses like Lassa virus (LASV), are fully resistant to its inhibitory e...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | английский |
| Опубликовано: |
2019
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| Online-ссылка: | https://doi.org/10.1371/journal.ppat.1007532 https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007532&type=printable |
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