Inhibiting xCT Improves 5-Fluorouracil Resistance of Gastric Cancer Induced by CD44 Variant 9 Expression

Cancer stem cells (CSCs) play a critical role in resistance to chemotherapy. CD44 is a cell surface marker of CSCs. CD44 variant 9 (CD44v9) interacts with a cystine-glutamate antiporter (xCT) and is an unfavorable predictive factor in gastric cancer. We investigated the impact of CD44v9 expression o...

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Huvudupphovsmän: Sawako Miyoshi, Hitoshi Tsugawa, Juntaro Matsuzaki, Kenro Hirata, Hideki Mori, Hideyuki Saya, Takanori Kanai∥, Hidekazu Suzuki
Materialtyp: Artigo
Språk:engelska
Publicerad: 2018
Länkar:https://doi.org/10.21873/anticanres.12969
https://ar.iiarjournals.org/content/anticanres/38/11/6163.full.pdf
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