Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients and 280,541 controls of European ancestry, from...

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Autors principals: Jūlı́us Guðmundsson, Jon K. Sigurdsson, Lilja Stefánsdóttir, Bjarni A. Agnarsson, Helgi J. Ísaksson, Ólafur Andri Stefánsson, Sigurjón A. Guðjónsson, Daníel F. Guðbjartsson, Gísli Másson, Michael L. Frigge, Simon Stacey, Patrick Sulem, Gísli H. Halldórsson, Vinicius Tragante, Hilma Hólm, Guðmundur I. Eyjólfsson, Ólöf Sigurðardóttir, Ísleifur Ólafsson, Þorvaldur Jónsson, Eiríkur Jónsson, Rósa B. Barkardóttir, Rafn Hilmarsson, Folkert W. Asselbergs, Guðmundur Geirsson, Unnur Þorsteinsdóttir, Þórunn Rafnar, Guðmar Þorleifsson, Kāri Stefánsson
Format: Artigo
Idioma:anglès
Publicat: 2018
Accés en línia:https://doi.org/10.1038/s41467-018-06920-9
https://www.nature.com/articles/s41467-018-06920-9.pdf
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