Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care

Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care

Older patients with newly diagnosed acute myeloid leukemia (AML) in the phase 3 AZA-AML-001 study were evaluated at entry for cytogenetic abnormalities, and a subgroup of patients was assessed for gene mutations. Patients received azacitidine 75 mg/m2/day x7 days (n = 240) or conventional care regim...

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Huvudupphovsmän: Hartmut Döhner, Anna Dolnik, Lin Tang, John F. Seymour, Mark D. Minden, Richard M. Stone, Teresa Bernal, Haifa Kathrin Al‐Ali, Valeria Santini, Paresh Vyas, C.L. Beach, Kyle J. MacBeth, Barry Skikne, S. Songer, Nora Tu, Lars Bullinger, Hervé Dombret
Materialtyp: Artigo
Språk:engelska
Publicerad: 2018
Länkar:https://doi.org/10.1038/s41375-018-0257-z
https://www.nature.com/articles/s41375-018-0257-z.pdf
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https://doi.org/10.1038/s41375-018-0257-z
https://www.nature.com/articles/s41375-018-0257-z.pdf

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