Cinobufacini protects against paclitaxel-induced peripheral neuropathic pain and suppresses TRPV1 up-regulation and spinal astrocyte activation in rats

Chemotherapy-induced peripheral neuropathic pain is a major limiting factor affecting cancer patients. No effective treatment is currently available. Cinobufacini, an aqueous extract from toad skin, is a widely used anti-cancer drug in China. Clinical evidence has demonstrated the safety and effecti...

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Detalhes bibliográficos
Principais autores: Xiyuan Ba, Jiali Wang, Shiyang Zhou, Xinxin Luo, Yun Peng, Shimin Yang, Yue Hao, Guangyi Jin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Acesso em linha:https://doi.org/10.1016/j.biopha.2018.09.018
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