Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression

Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression

Genome editing of human induced pluripotent stem cells (iPSCs) is instrumental for functional genomics, disease modeling, and regenerative medicine. However, low editing efficiency has hampered the applications of CRISPR-Cas9 technology in creating knockin (KI) or knockout (KO) iPSC lines, which is...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiaolan Li, Guohua Li, Juan Fu, Ya-Wen Fu, Lu Zhang, Wanqiu Chen, Cameron Arakaki, Jianping Zhang, Wei Wen, Mei Zhao, Weisheng V. Chen, Gary D. Botimer, David J. Baylink, Leslie Aranda, Hannah Choi, Rachel Bechar, Prue Talbot, Changkai Sun, Tao Cheng, Xiao‐Bing Zhang
Materyal Türü: Artigo
Dil:İngilizce
Baskı/Yayın Bilgisi: 2018
Online Erişim:https://doi.org/10.1093/nar/gky804
https://academic.oup.com/nar/article-pdf/46/19/10195/26333851/gky804.pdf
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Internet

https://doi.org/10.1093/nar/gky804
https://academic.oup.com/nar/article-pdf/46/19/10195/26333851/gky804.pdf

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