Persistent repair intermediates induce senescence
Abstract Double-stranded DNA breaks activate a DNA damage checkpoint in G2 phase to trigger a cell cycle arrest, which can be reversed to allow for recovery. However, damaged G2 cells can also permanently exit the cell cycle, going into senescence or apoptosis, raising the question how an individual...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Acesso em linha: | https://doi.org/10.1038/s41467-018-06308-9 https://www.nature.com/articles/s41467-018-06308-9.pdf |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|