Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy

Indoleamine 2,3-dioxygenase (IDO) is an immunoregulatory enzyme that metabolizes tryptophan to immunosuppressive kynurenines. We investigated whether IDO activity is associated with the size of HIV reservoir.Total human immunodeficiency virus (HIV) DNA in peripheral blood mononuclear cells (PBMCs) f...

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Main Authors: Jun Chen, Jingna Xun, Junyang Yang, Yongjia Ji, Li Liu, Tangkai Qi, Zhenyan Wang, Renfang Zhang, Yinzhong Shen, Rosalie Ponte, Vikram Mehraj, Jean‐Pierre Routy, Hongzhou Lu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Acesso em linha:https://doi.org/10.1093/cid/ciy676
https://academic.oup.com/cid/article-pdf/68/8/1274/28272317/ciy676.pdf
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