The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles

The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles

Endosomal sorting complex required for transport (ESCRT) complex proteins regulate biogenesis and release of extracellular vesicles (EVs), which enable cell-to-cell communication in the nervous system essential for development and adult function. We recently showed human loss-of-function (LOF) mutat...

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Bibliografiske detaljer
Main Authors: Michael E. Coulter, Cristina M. Dorobantu, Gerrald A. Lodewijk, François Delalande, Sarah Cianférani, Vijay Ganesh, Richard S. Smith, Elaine T. Lim, C. Shan Xu, Song Pang, Eric T. Wong, Hart G.W. Lidov, Monica L. Calicchio, Edward Yang, Dilenny M. Gonzalez, Thorsten M. Schlaeger, Ganeshwaran H. Mochida, Harald F. Hess, Wei-Chung Allen Lee, Maria K. Lehtinen, Tomas Kirchhausen, David Haussler, Frank M. J. Jacobs, Raphaël Gaudin, Christopher A. Walsh
Format: Artigo
Sprog:engelsk
Udgivet: 2018
Online adgang:https://doi.org/10.1016/j.celrep.2018.06.100
https://www.cell.com/article/S2211124718310428/pdf
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https://doi.org/10.1016/j.celrep.2018.06.100
https://www.cell.com/article/S2211124718310428/pdf

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