Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression
The impact of mitochondrial dysfunction in epigenetics is emerging, but our understanding of this relationship and its effect on gene expression remains incomplete. We previously showed that acute mitochondrial DNA (mtDNA) loss leads to histone hypoacetylation. It remains to be defined if these chan...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | anglais |
| Publié: |
2019
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| Accès en ligne: | https://doi.org/10.26508/lsa.201800228 https://www.life-science-alliance.org/content/lsa/2/1/e201800228.full.pdf |
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