Bioinformatic Expansion and Discovery of Thiopeptide Antibiotics

Thiopeptides are members of the ribosomally synthesized and post-translationally modified peptide family of natural products. Most characterized thiopeptides display nanomolar potency toward Gram-positive bacteria by blocking protein translation with several being produced at the industrial scale fo...

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Библиографические подробности
Главные авторы: Christopher J. Schwalen, Graham A. Hudson, Bryce Kille, Douglas A. Mitchell
Формат: Artigo
Язык:английский
Опубликовано: 2018
Online-ссылка:https://doi.org/10.1021/jacs.8b03896
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