Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers

Proviral integration Moloney virus (PIM) kinases (PIM1, 2 and 3) are overexpressed in several tumour types and contribute to oncogenesis. AZD1208 is a potent ATP-competitive PIM kinase inhibitor investigated in patients with recurrent or refractory acute myeloid leukaemia (AML) or advanced solid tum...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jorge E. Cortés, Kenji Tamura, Daniel J. DeAngelo, Johann S. de Bono, David Lorente, Mark D. Minden, Geoffrey L. Uy, Hagop M. Kantarjian, Lisa S. Chen, Varsha Gandhi, Robert Godin, Karen Keating, Kristen McEachern, Karthick Vishwanathan, J. Elizabeth Pease, Emma Dean
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2018
Mynediad Ar-lein:https://doi.org/10.1038/s41416-018-0082-1
https://www.nature.com/articles/s41416-018-0082-1.pdf
Tagiau: Ychwanegu Tag
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