Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers
Proviral integration Moloney virus (PIM) kinases (PIM1, 2 and 3) are overexpressed in several tumour types and contribute to oncogenesis. AZD1208 is a potent ATP-competitive PIM kinase inhibitor investigated in patients with recurrent or refractory acute myeloid leukaemia (AML) or advanced solid tum...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , , , , , , , , , , |
---|---|
Fformat: | Artigo |
Iaith: | Saesneg |
Cyhoeddwyd: |
2018
|
Mynediad Ar-lein: | https://doi.org/10.1038/s41416-018-0082-1 https://www.nature.com/articles/s41416-018-0082-1.pdf |
Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|