Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers
Proviral integration Moloney virus (PIM) kinases (PIM1, 2 and 3) are overexpressed in several tumour types and contribute to oncogenesis. AZD1208 is a potent ATP-competitive PIM kinase inhibitor investigated in patients with recurrent or refractory acute myeloid leukaemia (AML) or advanced solid tum...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
2018
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| ऑनलाइन पहुंच: | https://doi.org/10.1038/s41416-018-0082-1 https://www.nature.com/articles/s41416-018-0082-1.pdf |
| टैग: |
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