Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H ( <i>CFH</i> ) gene family
Significance Genetic variation of the complement factor H ( CFH ) gene family is associated with several complex diseases. Here, we have performed both long- and short-read sequencing of multiple humans and nonhuman primates in an effort to understand its complex evolutionary history. We find that t...
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Main Authors: | , , , , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | 英语 |
出版: |
2018
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在線閱讀: | https://doi.org/10.1073/pnas.1717600115 |
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