Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children

The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend optimal starting doses. Posaconazole plasma concentrations f...

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Autors principals: Sophida Boonsathorn, Iek Cheng, Frank Kloprogge, C. Alonso, Charmion Lee, Bilyana Doncheva, John Booth, Robert Chiesa, Adam Irwin, Joseph F. Standing
Format: Artigo
Idioma:anglès
Publicat: 2018
Accés en línia:https://doi.org/10.1007/s40262-018-0658-1
https://link.springer.com/content/pdf/10.1007/s40262-018-0658-1.pdf
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