B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex
GARP, a cell surface docking receptor for binding and activating latent TGF-β, is highly expressed by platelets and activated Tregs. While GARP is implicated in immune invasion in cancer, the roles of the GARP-TGF-β axis in systemic autoimmune diseases are unknown. Although B cells do not express GA...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
2018
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| Online Erişim: | https://doi.org/10.1172/jci.insight.99863 http://insight.jci.org/articles/view/99863/files/pdf |
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