The Light Chain Defines the Duration of Action of Botulinum Toxin Serotype A Subtypes
ABSTRACT Botulinum neurotoxin (BoNT) is the causative agent of botulism and a widely used pharmaceutical to treat a variety of neurological diseases. BoNTs are 150-kDa protein toxins organized into heavy chain (HC) and light chain (LC) domains linked by a disulfide bond. The HC selectively binds to...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , , |
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Fformat: | Artigo |
Iaith: | Saesneg |
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2018
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Mynediad Ar-lein: | https://doi.org/10.1128/mbio.00089-18 |
Tagiau: |
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