Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis

Rheumatoid arthritis (RA) is associated with an approximately two-fold elevated risk of cardiovascular (CV)-related mortality. Patients with RA present with systemic inflammation including raised circulating myeloid cells, but fail to display traditional CV risk-factors, particularly dyslipidaemia....

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Main Authors: Dragana Dragoljevic, Michael J. Kraakman, Prabhakara R. Nagareddy, Devi Ngo, Waled Shihata, Hélène L. Kammoun, Alexandra Whillas, Man Kit Sam Lee, Annas Al‐Sharea, Gerard Pernes, Michelle Flynn, Graeme I. Lancaster, Mark A. Febbraio, Jaye Chin‐Dusting, Beatriz Y. Hanaoka, Ian P. Wicks, Andrew Murphy
格式: Artigo
语言:英语
出版: 2018
在线阅读:https://doi.org/10.1093/eurheartj/ehy119
https://academic.oup.com/eurheartj/article-pdf/39/23/2158/25041461/ehy119.pdf
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