Phospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy
Tau is a microtubule-associated protein which regulates the assembly and stability of microtubules in the axons of neurons. Tau is also a major component of neurofibrillary tangles (NFTs), a pathological hallmark in Alzheimer's disease (AD). A characteristic of AD tau is hyperphosphorylation wi...
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| Main Authors: | , , , |
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| 格式: | Revisão |
| 語言: | 英语 |
| 出版: |
2018
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| 在線閱讀: | https://doi.org/10.3389/fnins.2018.00044 https://www.frontiersin.org/articles/10.3389/fnins.2018.00044/pdf |
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