Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells
Human pluripotent stem cell (hPSC) lines are known to have a bias in their differentiation. This gives individual cell lines a propensity to preferentially differentiate towards one germ layer or cell type over others. Chromosomal aberrations, mitochondrial mutations, genetic diversity and epigeneti...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | 英語 |
| 出版事項: |
2017
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| オンライン･アクセス: | https://doi.org/10.1093/humupd/dmx042 https://academic.oup.com/humupd/article-pdf/24/2/162/24149710/dmx042.pdf |
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