Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells
Human pluripotent stem cell (hPSC) lines are known to have a bias in their differentiation. This gives individual cell lines a propensity to preferentially differentiate towards one germ layer or cell type over others. Chromosomal aberrations, mitochondrial mutations, genetic diversity and epigeneti...
Sábháilte in:
| Príomhchruthaitheoirí: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
2017
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| Rochtain ar líne: | https://doi.org/10.1093/humupd/dmx042 https://academic.oup.com/humupd/article-pdf/24/2/162/24149710/dmx042.pdf |
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