Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties

Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties

Intestinal stem cells (ISCs) play indispensable roles in the maintenance of homeostasis, and also in the regeneration of the damaged intestinal epithelia. However, whether the inflammatory environment of Crohn's disease (CD) affects properties of resident small intestinal stem cells remain unce...

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Bibliografski detalji
Glavni autori: Kohei Suzuki, Tatsuro Murano, Hiromichi Shimizu, Go Ito, Toru Nakata, Satoru Fujii, Fumiaki Ishibashi, Ami Kawamoto, Sho Anzai, Reiko Kuno, Konomi Kuwabara, Junichi Takahashi, Minami Hama, Sayaka Nagata, Yui Hiraguri, K Takenaka, Shiro Yui, Kiichiro Tsuchiya, Tetsuya Nakamura, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto
Format: Artigo
Jezik:engleski
Izdano: 2018
Online pristup:https://doi.org/10.1007/s00535-018-1437-3
https://link.springer.com/content/pdf/10.1007%2Fs00535-018-1437-3.pdf
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Internet

https://doi.org/10.1007/s00535-018-1437-3
https://link.springer.com/content/pdf/10.1007%2Fs00535-018-1437-3.pdf

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