Sulforaphane metabolites cause apoptosis via microtubule disruption in cancer

Sulforaphane (SFN) inhibited growth in many cancers, but its half-life is 2 h in circulation. However, its metabolites, sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl-cysteine (SFN-NAC) had longer half-lives and decreased the cell viability in both dose- and time-dependent manners in huma...

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Bibliographic Details
Main Authors: Yan Zhou, Gaoxiang Yang, Hua Tian, Yabin Hu, Sai Wu, Geng Yang, Kai Lin, Wei Wu
Format: Artigo
Language:English
Published: 2018
Online Access:https://doi.org/10.1530/erc-17-0483
https://erc.bioscientifica.com/downloadpdf/journals/erc/25/3/ERC-17-0483.pdf
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