Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase
Tyrosinase is the rate-limiting enzyme of melanin production and, accordingly, is the most prominent target for inhibiting hyperpigmentation. Numerous tyrosinase inhibitors have been identified, but most of those lack clinical efficacy because they were identified using mushroom tyrosinase as the ta...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2018
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| Online Access: | https://doi.org/10.1016/j.jid.2018.01.019 http://www.jidonline.org/article/S0022202X18301003/pdf |
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