Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase

Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase

Tyrosinase is the rate-limiting enzyme of melanin production and, accordingly, is the most prominent target for inhibiting hyperpigmentation. Numerous tyrosinase inhibitors have been identified, but most of those lack clinical efficacy because they were identified using mushroom tyrosinase as the ta...

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Huvudupphovsmän: Tobias Mann, Wolfram Gerwat, Jan Batzer, Kerstin Eggers, Cathrin Scherner, Horst Wenck, Franz Stäb, Vincent J. Hearing, Klaus‐Heinrich Röhm, Ludger Kolbe
Materialtyp: Artigo
Språk:engelska
Publicerad: 2018
Länkar:https://doi.org/10.1016/j.jid.2018.01.019
http://www.jidonline.org/article/S0022202X18301003/pdf
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https://doi.org/10.1016/j.jid.2018.01.019
http://www.jidonline.org/article/S0022202X18301003/pdf

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